Abstract: To solve the problems of power loss and voltage deviation in regional energy control, improve the on-site consumption level of renewable energy. Builds an Interline Power Flow Controller (IPFC) model and analyzes its operating mode. The Krill-Herd algorithm is used to predict the renewable energy capacity, based on the voltage stability index and line utilization. The Newton-Raphson method of power flow analysis is performed on the improved IEEE 30-bus system. By adjusting the parameters of the power flow controller between the lines to reduce the active power loss and voltage deviation of the integrated energy system. The experimental results show that compared to traditional power plants, the method proposed in this paper reduces active power loss by 18.56%, reactive power loss by 14.72%, and voltage deviation by 41.55%, effectively improving the operational performance and economy of IPFC for regional energy systems. It provides a reliable method for the application of regional energy optimization control technology.