Abstract: From the perspective of multi-energy complementarity and synergy, a systematic exploration is conducted on the planning and design methods for the comprehensive energy system of a zero-carbon industrial park. Firstly, the national energy policy requirements for zero-carbon industrial parks are systematically interpreted. Secondly, based on the analysis of the characteristics of the traditional industrial park's energy system, requirements for the construction of the zero-carbon industrial park's comprehensive energy system are provided regarding energy structure, energy efficiency improvement, digital control, carbon management, and regional collaboration. Finally, through case analysis, specific planning and design points and specific practices are given in a targeted manner. The research conclusion indicates that from the perspective of multi-energy complementarity and synergy, the zero-carbon industrial park's comprehensive energy system needs to be constructed with wind, solar, hydrogen, and storage as the core, through multi-energy coupling of electricity, heat, and hydrogen and digital control to achieve an energy cascade utilization rate increase of more than 30%. Relying on the full life cycle carbon management mechanism and regional power market collaboration, the final goal of achieving a renewable energy proportion of ≥70% and precise carbon neutrality can be achieved.