Abstract: Arc fault protection technology is an important research direction in the field of electrical safety. Under the condition of arc fault occurrence, how to achieve fast and accurate calculation and trends prediction of arc fault protection through simulation analysis to reduce the number of on-site tests, reduce research and development costs, and achieve better product design is an urgent need in current engineering projects. In this study, the arc fault protection analysis requirements of general medium voltage drive cabinet under arc fault conditions in industrial application are expounded, a fast simulation analysis method of the arc fault protection in medium voltage drive cabinet is proposed. This method is used to access the structural strength and connection reliability of MVD cabinet, it is suitable for rapid and accurate analysis and verification in engineering design to achieve efficient improvement of medium voltage drive cabinet design. The finite element analysis software ANSYS Workbench is used to perform this simulation. Based on the requirements of standard IEC 62477-2, on-site arc fault test of medium voltage drive cabinet is conducted. At the same time, the engineering calculations of arc fault protection in medium voltage drive cabinet are performed. Simulation analysis results are compared with on-site test data and engineering calculation results. The rationality and reliability of the simulation analysis method have been